The Nebraska Healthcare Collaborative fosters data-driven innovation to improve the health of patients and populations through a unique health data infrastructure. Our team curates valuable health data marts from the statewide Health Data Utility which includes electronic health records, social service referrals, prescription monitoring, claims data, and more. Our data repository is comprehensive, and current creating a unique opportunity for researchers, policy makers, and public health organizations to access longitudinal health data, while balancing the privacy and confidentiality of patient information. This infrastructure has supported numerous investigations into public health concerns and health outcome improvements within Nebraska and across the country.